Researcher:
Sözmen, Banu Oflaz

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Faculty Member

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Banu Oflaz

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Sözmen

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Sözmen, Banu Oflaz

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2014 - 2019122020 - 20225

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Researcher Of Publications: search.filters.isAuthorOfPublication.d7e2d2f8-5207-4037-b146-00aaaf3d2a86

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Now showing 1 - 10 of 17
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    A case of secondary hemophagocytic lymphohistiocytosis (HLH) following incomplete kawasaki's disease (KD). Importance of distinguishing recurrent kd from HLH
    (2014) Kebudi, R.; Dindar, A.; Gürakan, F.; Devecioğlu, O.; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
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    Evaluation of coagulation tests before newborn circumcision: is it necessary?
    (Lippincott Williams & Wilkins, 2016) Kayiran, Sinan Mahir; N/A; Eroğlu, Egemen; Sözmen, Banu Oflaz; Albayrak, Selvinaz; Gürakan, Berkan Ali; Faculty Member; Faculty Member; Teaching Faculty; Faculty Member; School of Medicine; School of Medicine; School of Nursing; School of Medicine; Koç University Hospital; 214688; 198711; 106119; 196431
    Evaluation of coagulation parameters prior to newborn circumcision is routinely performed in many countries. However, the value of this screening in predicting the bleeding risk is unknown. The aim of this study was to evaluate the correlation between the preoperative prolonged prothrombin time (PT), activated partial thromboplastin time (aPTT) and excessive bleeding after the circumcision in term, healthy newborns without family history of coagulopathy. The medical records of healthy, full term newborns born at VKV American Hospital, in Istanbul, Turkey, between 2009 and 2012 who were circumcised within the first week of life, were reviewed retrospectively. The data for family history of coagulopathy, clinical sign(s) of bleeding during and/or after delivery, preoperative PT, aPTT levels and the amount of bleeding after circumcision were gathered. The most recent medical records of the patients' were also reviewed for any possible, lately diagnosed bleeding disorder. A total of 450 newborns met the above criteria. None had a family history of bleeding disorder or clinical bleeding. A total of 158 (35%) newborns had an aPTT result greater than 54.5s, 269 (59%) had PT result greater than 15.9 s and 72 (16%) had international normalized ratio result greater than 1.62. Neither of the patients with prolonged PT and/or aPTT had prolonged or excessive bleeding. The evaluation of PT and aPTT before elective newborn circumcision is not necessary in the absence of clinical bleeding or a family history of bleeding disorder. It is rather a habit in general practice and possibly a result of defensive medicine. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
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    Prolonged extracorporeal membrane oxygenation in pediatric leukemia with severe acute respiratory distress syndrome and persistent fungemia
    (Wiley, 2021) Kebudi, Rejin; Bahar, Mois; Paker, Tufan; Hacı, İsmail; Ekinci, Alim; Egeli, Demet; Eren, Özge; İnel, Yalçın; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
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    Infections with respiratory viruses in children with cancer in Istanbul at the last year
    (Wiley-Blackwell, 2015) Bay, S. Büyükkapu; Kebudi, R.; Görgün, O.; Koç, B.; Zülfikar, B.; Badur, S.; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
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    Breast metastases in rhabdomyosarcoma: a case series
    (Wiley, 2015) Kebudi, R.; Koç, B.; Görgün, O.; Bay, S. Büyükkapu; Çakır, F. B.; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
    Metastasis to the breast in the pediatric age group is extremely rare. After leukemia and lymphoma, rhabdomyosarcoma and neuroblastoma are the most common tumors to metastasize to the breast in this age group. Without a known primary, the diagnosis can be a challange. Here, a pediatric patient with widespread metastases to both breasts from embryonal rhabdomyosarcoma imaged by ultrasound and magnetic resonance is presented.
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    Larotrectinib in NTRK fusion-positive locally advanced or metastatic soft tissue sarcomas in children: a case series
    (Wiley, 2021) Buyukkapu, S. Bay; Kebudi, R.; Asarcıklı, Fikret; Sözmen, Banu Oflaz; Erbey, Mehmet Fatih; Doctor; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; Koç University Hospital; N/A; 198711; 206213
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    Comparative analysis of autophagy in drug responses and aggressive behavior of adult versus pediatric glioma cell lines
    (Wiley, 2022) Aygun, Bera; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Yenidoğan, İrem; Peker, Nesibe; Deveci, Gamze; Kırmızı, Döndü; Asarcıklı, Fikret; Sözmen, Banu Oflaz; Akyoldaş, Göktuğ; Kulaç, İbrahim; Solaroğlu, İhsan; Erbey, Mehmet Fatih; Gözüaçık, Devrim; Researcher; Researcher; PhD Student; Other; Doctor; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; N/A; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; School of Medicine; N/A; Graduate School of Health Sciences; N/A; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 327591; N/A; N/A; N/A; N/A; 198711; 203677; 102059; 206213; 40248
    Central nervous system tumors are the most common solid cancer and a leading cause of cancer-related deaths in children. Glioma is the most challenging pediatric CNS tumor with therapy resistance and poor prognosis in pediatric patients. Although histopathological analyses revealed similarities with adult brain glioma, emerging evidence suggests that the deregulated molecular pathways in pediatric glioma (p-GM) are different from that of adults. Autophagy, a cellular clearance system and a drug resistance mechanism, has been implicated in glioma progression, invasion, and relapse, yet its role in pediatric patients is not well documented. In this study, we compared the autophagic capacity of adult versus p-GM cell lines and evaluated the effect of autophagy manipulation on drug responses. In addition, migration, extracellular matrix invasion ability, and the metabolism of pediatric and adult gliomas were compared and the contribution of autophagy to the aggressive phenotype was evaluated.
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    Children with neuroendocrine tumors presenting with opsoclonus myoclonus syndrome
    (Wiley-Blackwell, 2016) Kebudi, R.; Uysal, S.; Eroğlu, E.; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
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    Infections with respiratory viruses in children with cancer in Istanbul
    (Wiley-Blackwell, 2014) Kebudi, R.; Kapu, S. Bay; Ciblak, M.; Görgün, O.; Zülfikar, B.; Badur, S.; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
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    Childhood ganglioneuromas
    (Wiley, 2016) Kebudi, R.; Çakır, F. B.; Görgün, O.; Bilgiç, B.; Sözmen, Banu Oflaz; Faculty Member; School of Medicine; 198711
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