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Data the DEHP induced changes on the trace element and mineral levels in the brain and testis tissues of rats

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SCHOOL OF MEDICINE
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Karabulut, Gözde
Gök, Müslüm
Barlas, Nurhayat Emir

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NO

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Abstract

Di (2-ethylhexyl) phthalate (DEHP) is used as plasticizer in the industry and belongs to the phthalate family which can induce tissue damage including kidney, liver, and testis as a result of elevated oxidative stress levels. Glutathione reductase (GR), Glucose-6-phosphate dehydrogenase (G6PD), glutathione S-transferase (GST), 6-phosphogluconate dehydrogenase (6PGD), enzyme activities, trace element and mineral levels were evaluated in the brain and testis tissue samples. Our data revealed that, antioxidant enzyme activities in the brain and testis samples were statistically insignificant in the DEHP administered groups compared to the control group except 400 mg/kg/day DEHP dose group in the testis samples. DEHP can disrupt trace element and mineral levels unlike antioxidant enzyme levels that may due to blood-brain and testis-blood barrier and/or short-term exposure to the DEHP. For more detailed information than the data presented in this Journal article, please see the research Journal article “Impact of the di (2-Ethylhexyl) phthalate administration on trace element and mineral levels in relation of kidney and liver damage in rats” [1].

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Elsevier

Subject

Medicine, Medical biochemistry

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Data in Brief

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DOI

10.1016/j.dib.2019.104526

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