Researcher: Ağcaoğlu, Orhan
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Ağcaoğlu, Orhan
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Publication Metadata only Robotic versus laparoscopic adrenalectomy: the European experience(Springer, 2022) Vatansever, Safa; Makay, Özer; Ağcaoğlu, Orhan; Faculty Member; School of Medicine; 175476Purpose of Review To summarize the current European-based literature and find answers regarding whether there is any specific condition in which robotic adrenalectomy is superior. Recent Findings For the resection of the adrenal glands, laparoscopic adrenalectomy is the gold standard technique worldwide. With the widespread use of robotic technology in surgery, robotic adrenalectomy has become more popular. The safety and feasibility of robotic adrenalectomy has been shown in several studies. However, despite its technical advantages, robotic surgery has not yet shown a significant supremacy over laparoscopic surgery in terms of surgical outcomes. Summary The robotic adrenalectomy is a safe and feasible technique, similar to conventional laparoscopic adrenalectomy. Patients with specific conditions may benefit from robotic surgery. Yet, the high-quality data are still scant.Publication Metadata only Should we perform routine prophylactic central neck dissection in patients with thyroid papillary microcarcinoma?(Edizioni Luigi Pozzi, 2018) Bilgiç, Cağrı; Karabay, Önder; Ağcaoğlu, Orhan; Şengün, Berke; Özoran, Emre; Taşkın, Orhun Çığ; Dereli, Dilek Yazıcı; Tezelman, Tevfik Serdar; Faculty Member; Undergraduate Student; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 175476; N/A; N/A; 166686; 179659; 114860PURPOSE: Cervical lymph node (LN) metastases in papillary thyroid cancer (PTC) are common in tumors especially that are larger than 1cm. Ipsilateral central neck dissection (CND) is usually preferred even in the absence of a palpable LN. This study aims to clarify the incidence and predictive factors for occult ipsilateral central LN metastasis in these patients, and the management of patients without clinical evidence of metastasis. METHODS: 204 PTC patients were studied. The patients were divided into two according to the tumor size of <= 5mm or larger. Patient demographics, tumor properties, LN metastasis, preoperative neck ultrasonography findings and surgical outcomes were analyzed. RESULTS: There were 152 patients in study group-1 (nodule > 5 mm) and 52 patients in group-2 (nodule 5 mm). The mean tumor size was 11.9 mm. Overall, preoperative neck ultrasonography showed central neck LN in 25 (12.3%) patients, however, final pathology revealed metastatic LN at central compartment in 59 (28.9%) patients. There were 56 (27.5%) patients with metastasis in group-1 compared to 3 (1.4%) patients in group-2. CONCLUSIONS: Prophylactic CND is advised in PTC for the reduction of recurrence in central compartment. According to our results, in patients with tumors smaller than 5 mm and without evidence of nodal metastasis in preoperative neck ultrasonography, we do not recommend prophylactic CND.Publication Metadata only Robotic complete mesocolic excision for transverse colon cancer can be performed with a morbidity profile similar to that of conventional laparoscopic colectomy(Springer, 2020) Özben, Volkan; De Muijnck, Cansu; Zenger, Serkan; Aytac, Erman; Bilgin, İsmail Ahmet; Baca, Bilgi; Hamzaoğlu, İsmail; Karahasanoğlu, Tayfun; N/A; N/A; N/A; N/A; Şengün, Berke; Ağcaoğlu, Orhan; Balık, Emre; Buğra, Dursun; Undergraduate Student; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 309087; 175476; 18758; 1758Background: In minimally invasive surgery, complete mesocolic excision (CME) for transverse colon cancer is challenging; thus, non-CME resections are commonly preferred when laparoscopy is used. Robotic technology has been developed to reduce the limitations of laparoscopy. The aim of our study was to evaluate whether robotic CME for transverse colon cancer can be performed with short-term outcomes similar to those of laparoscopic conventional colectomy (CC). Methods: A retrospective review of 118 consecutive patients having robotic CME or laparoscopic CC for transverse colon cancer in two specialized centers between May 2011 and September 2018 was performed. Perioperative 30-day outcomes of the two procedures were compared. Results: There were 38 and 80 patients in the robotic CME group and laparoscopic CC group, respectively. The groups were comparable regarding preoperative characteristics. Intraoperative results were similar, including blood loss (median 50 vs 25 ml), complications (5.3% vs 3.8%), and conversions (none vs 7.5%). The rate of intracorporeal anastomosis was significantly higher (86.8% vs 20.0%), mean operative time was longer (325.0 +/- 123.2 vs 159.3 +/- 56.1 min (p < 0.001), and the mean number of harvested lymph nodes was higher in the robotic CME group (46.1 +/- 22.2 vs 39.1 +/- 17.8, p = 0.047). There were only minor differences in length of hospital stay (7.2 +/- 3.1 vs 7.9 +/- 4.0 days), anastomotic leak (none vs 2.6%), bleeding (none vs 1.3%), surgical site infections (10.5% vs 12.5%), and reoperations (2.6% vs 6.3%). Conclusions: Robotic CME can be performed with a similar morbidity profile as laparoscopic CC for transverse colon cancer along with a higher rate of intracorporeal anastomosis, and higher number of lymph nodes retrieved, but longer operative times.Publication Metadata only Predictive factors of operative hemodynamic instability for pheochromocytoma(Southeastern Surgical Congress, 2018) Aksakal, Nihat; Sahbaz, Nuri Alper; Albuz, Ozgur; Saracoglu, Ayten; Yavru, Aysen; Barbaros, Umut; Erbil, Yesim; Ağcaoğlu, Orhan; Faculty Member; School of Medicine; 175476Pheochromocytoma is an uncommon catecholamine-secreting tumor in which resection is often associated with hemodynamic instability (HI). In this study, we aim to clarify the factors affecting surgical HI in patients who underwent surgery with the diagnosis of pheochromocytoma. All patients who underwent surgery with the diagnosis of pheochromocytoma between 2008 and 2015 were analyzed retrospectively. Patients with inconsistent diagnosis or missing outcomes and follow-up data were excluded. A total of 37 patients were included in this study. Patient demographics, operative time, tumor size, period of medical treatment until surgery, catecholamine levels in urine, and HI patterns were analyzed. There were 23 (62%) male and 14 (38%) female patients. Hemodynamic instability occurred in 13 (35%) patients. Overall, HI was higher in patients with tumor size <6 cm (P < 0.02); moreover, urine catecholamine levels were detected significantly higher than a cutoff value of 2000 mu g/24 hours in hemodynamically instable group. In this study, tumor diameter of <6 cm and urine catecholamine levels >2000 mu g/24 hours were associated with HI. Preoperative management is essential for preventing hypertensive crisis and HI before or during surgery.Publication Metadata only Totally robotic versus totally laparoscopic surgery for rectal cancer(LIPPINCOTT WILLIAMS & WILKINS, 2018) Esen, Eren; Aytaç, Erman; Zenger, Serkan; Baca, Bilgi; Hamzaoğlu, İsmail; Karahasanoğlu, Tayfun; Ağcaoğlu, Orhan; Balık, Emre; Buğra, Dursun; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; 175476; 18758; 1758In this study, perioperative and short-term postoperative results of totally robotic versus totally laparoscopic rectal resections for cancer were investigated in a comparative manner by considering risk factors including obesity, male sex, and neoadjuvant treatment. In addition to overall comparison, the impact of sex, obesity (body mass index >= 30 kg/m(2)), and neoadjuvant treatment was assessed in patients who had a total mesorectal excision (TME). Operative time was longer in the robotic group (P<0.001). In obese patients who underwent TME, the mean length of hospital stay was shorter (7 +/- 2 vs. 9 +/- 4 d, P=0.01), and the mean number of retrieved lymph nodes was higher (30 +/- 19 vs. 23 +/- 10, P=0.02) in the robotic group. Totally robotic and totally laparoscopic surgery appears to be providing similar outcomes in patients undergoing rectal resections for cancer. Selective use of a robot may have a role for improving postoperative outcomes in some challenging cases including obese patients undergoing TME.Publication Metadata only Ultrasound-guided bilateral erector spinae plane block versus tumescent anesthesia for postoperative analgesia in patients undergoing reduction mammoplasty: a randomized controlled study(Springer, 2019) N/A; N/A; Oğuz, Bahadır Hakan; Gürkan, Yavuz; Ağcaoğlu, Orhan; Erçelen, Ömür; Other; Faculty Member; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; N/A; 154129; 175476; 12305PurposeThe aim of this prospective, randomized, double-blind study was to compare the tumescent anesthesia method and erector spinae block with respect to postoperative analgesia consumption, pain scores and patient satisfaction, in patients receiving breast reduction surgery under general anesthesia. MethodsThe study included 44 females, aged 20-65years, who were to undergo breast reduction surgery, without adjunctive liposuction on the breast. Using the closed envelope method, the patients were randomly separated into two groups to receive tumescent anesthesia or erector spinae block (ESB). Patients in the ESB group received the block before general anesthesia by a single anesthetist (G.o.).ResultsThe 24-h tramadol consumption with PCA, which was the primary outcome of the study, was determined to be statistically significantly less in the ESB group (p<0.001). The NRS scores were compared at 30min postoperatively and then at 1, 2, 4, 6, 12 and 24h. At all the measured time points, the pain scores of the ESB group were statistically significantly lower (p<0.001). Additional analgesia was required by one patient in the ESB group and by seven patients in the tumescent group and was applied as 1g paracetamol. The requirement for additional analgesia was statistically significantly lower in the ESB group (p<0.024). Patient satisfaction was statistically significantly better in the ESB group (p<0.001).ConclusionsAccording to the results of this study, bilateral ESB performed under ultrasound guidance in breast reduction surgery was more effective than tumescent anesthesia concerning postoperative analgesia consumption and pain scores. ESB could be an appropriate, effective and safe postoperative analgesia method for patients undergoing reduction mammoplasty surgery.Level of Evidence IIThis journal requires that authors assign a level of evidence to each articlePublication Metadata only Bilateral rhomboid block may provide complete pain relief following bilateral breast surgery(Elsevier Science Inc, 2021) N/A; N/A; N/A; N/A; N/A; N/A; N/A; Gürkan, Yavuz; Manici, Mete; Salgın, Belitsu; Dilege, Ece; Ağcaoğlu, Orhan; Tatar, Sedat; Erçelen, Ömür; Faculty Member; Faculty Member; Researcher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; 154129; 113502; 327625; 218050; 175476; N/A; 12305N/APublication Metadata only Role of spect/ct in detection of the marked metastatic lymph node and the sentinel node, after neoadjuvant chemotherapy in patients with breast cancer(Churchill Livingstone, 2021) N/A; N/A; N/A; N/A; Dilege, Ece; Falay, Fikri Okan; Ağcaoğlu, Orhan; Kapucuoğlu, Fatma Nilgün; Faculty Member; Teaching Faculty; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 218050; 246484; 175476; 7421N/APublication Metadata only Live surgical demonstrations for minimally invasive colorectal training(Springer, 2020) N/A; N/A; Özoran, Emre; Ağcaoğlu, Orhan; Balık, Emre; Buğra, Dursun; Teaching Faculty; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 307296; 175476; 18758; 1758Purpose Live surgical demonstrations are considered an effective educational tool providing a chance for trainees to observe a real-time decision-making process of expert surgeons. No data exists evaluating the impact of live surgical demonstrations on the outcomes of minimally invasive colorectal surgery. This study evaluates perioperative and short-term postoperative outcomes in patients undergoing minimally invasive colorectal surgery in the setting of live surgical demonstrations. Methods Patients undergoing minimally invasive colorectal surgery which was performed as live surgical demonstrations (the study group) performed between 2006 and 2018 were reviewed. These patients were case-matched with those undergoing operations in routine practice (the control group). The study and control group were compared for intraoperative and short-term postoperative outcomes. Results Thirty-nine live surgery cases in the study group were case-matched with its thirty-nine counterparts as the control group. Operating time was longer (200 vs 165 min; p = 0.002) and estimated intraoperative blood loss was higher in the study group (100 vs 55 ml; p = 0.008). Patients in the study group stayed longer in the hospital (6 vs 5 days; p = 0.001). While conversion (n = 4 vs n = 1, p = 0.358) and intraoperative complications (n = 6 vs n = 2, p = 0.2) were more frequent in the study group, these outcomes did not reach statistical significance. Overall complications were higher in the study group (n = 22 vs n = 9, p = 0.003). One patient underwent a reoperation due to postoperative bleeding, and one mortality occurred in the live surgery group. Conclusions Live surgical demonstrations in minimally invasive colorectal surgery seem to be associated with increased risk of operative morbidity.Publication Metadata only Robotic adrenalectomy(Springer, 2019) Makay, Ozer; N/A; Ağcaoğlu, Orhan; Faculty Member; School of Medicine; 175476Purpose Even though laparoscopy is still the gold standard technique of adrenal surgery, many of the recent reports noted the safety and efficacy of robotics. However, there are still scant data and debates regarding outcomes of robotics in adrenal surgery. The aim of this review was to discuss recent literature and provide institutional experience on robotic adrenalectomy.Recent Findings Due to improved maneuverability, robotics have certain advantages especially in patients with large tumors or those needing fine dissection; however, longer operative times and increased costs are still major drawbacks for this technique.Summary By excluding the disadvantages of conventional techniques, enhanced 3-dimensional view, articulated instrumentation, and comfort makes the robotic technique more striking. Although the use of robotic system has increased since 2010, we expect that the increase in use will continue as newer technologies and advanced surgical techniques pervade all corners of oncologic care.